This condition is common among patients who lose muscle mass and strength from a lack of movement for extended periods of time, such as patients recovering from hip fractures, those in intensive care, and the elderly. National Laboratory in hopes of improving treatments for patients on Earth with disuse muscle atrophy. Se-Jin Lee, sent 40 female mice to the ISS U.S. The research team, led by Principal Investigator Dr. The experiment returned to Earth earlier today when the Dragon spacecraft splashed down in the Pacific Ocean. What does it take to turn a run-of-the-mill, average laboratory mouse into a Mighty Mouse? More than just a mouse-sized superhero costume, according to researchers at The Jackson Laboratory who launched an experiment to the International Space Station (ISS) on SpaceX’s 19 th commercial resupply services mission last month. Such research is particularly important for conditions that involve muscle wasting due to immobility or reduced activity, such as in patients recovering from hip fracture surgery, intensive care patients, and the elderly.This research could provide valuable preclinical data to support clinical trials for myostatin therapies for a wide range of conditions that affect muscle and bone health.The investigation seeks to examine the potential benefits of targeting the myostatin and activin signaling pathways to prevent skeletal muscle and bone loss.These Mighty Mice have twice the muscle mass of normal mice that possess the gene for producing myostatin.Researchers from The Jackson Laboratory sent 40 mice to the ISS National Lab, including some “Mighty Mice” that lack the gene for producing the growth factor myostatin.To read the IRS Form 990 (2018), click here. As with most research laboratories, JAX spends a lot on staff compensation because at the heart of the organization’s mission is research conducted by employees. In summary, JAX is a well funded organization with a strong financial foundation. It is worth noting JAX posted a $38 million dollar unrealized loss on investments in 2018 which means the general fund balance would have been considerably higher if this loss did not occur. Collectively, JAX spent $77 out of every $100 in revenue reported, allocating the remaining revenue ($23 out of every $100) to the general fund which had $740 million at year-end. Using the above information, every $100 in revenue was spent as follows:Īs illustrated above, nearly half of revenue was spent on staff compensation. JAX spent $77 out of every $100 raised in 2018, with the unspent revenue added to the general fund, which had a $740 million net asset balance at year-end. $58 million, or 13% of revenue was spent on supplies followed by $29 million (7% of revenue) on Office-Related Expenses. Given that the organization is focused on research, it is not surprising that compensation is the largest expense. ![]() 2,557 employees received $206 million, or 48% of revenue, as compensation, which means the average compensation was $81,000. ![]() $ 9 million (2% of revenue): Travel and ConferencesĪs illustrated above, compensation is the largest expense for JAX.advertising and promotion, royalties, interest, etc) $ 14 million (3% of revenue): Other Expenses (i.e.$ 16 million (4% of revenue): Fees for Services.$ 29 million (7% of revenue): Office-Related Expenses. ![]()
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